135 Mycobacterial Infections in cChildren With Chronic Granulomatous Disease
نویسندگان
چکیده
immunohistochemistry.Human turbinates were obtained after turbinectomy from 6 patients with nasal obstruction refractory to medical therapy. Total RNA was isolated from human nasal mucosa, and CysLT2 receptor mRNA was detected in these tissues by using reverse transcriptase-PCR analysis. To identify the cells expressing CysLT2 receptor protein, double immunostaining was performed using anti-CysLT2 receptor antibody and anti-CD31 (endothelial cell) antibody. Results: Reverse transcriptase-PCR analysis of total nasal RNA demonstrated the expression of CysLT2 receptor mRNA. The immunohistochemical studies revealed that anti-CysLT2 receptor antibody mainly labeled blood vessels. Conclusions: The results suggest a primary role for CysLT2 receptor as the vascular responses in upper respiratory tract.
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